Immunohistochemistry (IHC) Histopathology Services
At GlintLab, we provide fully automated Immunohistochemistry (IHC) workflows designed to deliver consistent, high-quality results across a variety of therapeutic areas and research pathways. Our expertise includes antibody optimization and the development of both single-plex and multiplex IHC protocols tailored to your study’s needs.
Why Choose GlintLab for IHC?
- Advanced Automation: We utilize state-of-the-art Leica Bond and Roche Ventana Discovery Ultra autostainers, enabling precision and reproducibility in staining across diverse tissue types and applications.
- Flexible Solutions: Our services accommodate both single-plex IHC for targeted analysis and multiplex IHC for simultaneous detection of multiple markers, depending on marker compatibility, tissue characteristics, and study objectives.
- Quantitative Data Outputs: Whether you require qualitative assessments or quantitative data to inform your research, we can customize protocols to meet your specific goals.
Therapeutic Areas and Immunohistochemistry (IHC) Marker Expertise
Our extensive library of optimized protocols spans several key research areas:
Immuno-Oncology marker examples: CD3, CD4, CD8, CD68, FoxP3, PD1, PDL1, CD45, CD11b, CD11c, CD20, CD103, CD14, CD163, CD19, CD206 and more…
Neuroscience: GFAP, Iba1, NeuN, S100β, NF-M, MBP
Dermatology: COL1A1, Perilipin-1, CD31
Respirology: SMA, E-cadherin, Cytokeratin 5, Acetylated Tubulin, MUC5B
Rare Disease: Laminin, Dystrophin
Epitope Tags/Fusion Proteins: HA Tag, GFP, Luciferase, mCherry
Apoptosis: Cleaved Caspase 3, Cleaved Caspase 8, Cleaved Caspase 9, Cleaved PARP or TUNEL assay
Proliferation: PCNA, Ki67
Customized Protocol Development
We collaborate closely with clients to optimize staining protocols based on:
- Marker selection: Ensuring compatibility for desired pathways or therapeutic targets.
- Tissue type: FFPE or frozen sections from human or animal models.
- Study goals: From exploratory research to preclinical studies.
Our team’s expertise extends to developing protocols for advanced IHC techniques, such as multiplex staining for spatial biomarker analysis, and ensuring reproducibility across runs for publication-quality data.
Multiplex IHC for Complex Insights
For clients exploring complex tissue microenvironments or co-localization of biomarkers, we offer multiplex IHC workflows using chromogenic detection. These methods enable:
- Detailed characterization of immune cell infiltration in tumor microenvironments.
- Spatial mapping of neural or inflammatory markers in tissue sections.
Connect With Us
With our rigorous quality control standards and commitment to scientific excellence, GlintLab is your trusted partner for generating actionable insights from tissue-based assays.
Contact us today to discuss how we can support your research goals with tailored IHC solutions!
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